Rio Ferdinand, John O’Shea, Jonny Evans and Fabio will be missing when Manchester United take on Besiktas (Man United 2/5 draw 10/3 Besiktas 15/2 match bets) in a Champions League dead-rubber at Old Trafford on Wednesday.

Sir Alex Ferguson revealed on Tuesday he had no alternative but to start with the same defence – Rafael, Wes Brown, Nemanja Vidic and Patrice Evra – that helped beat Everton at the weekend for the European visit of the Turks.

The Old Trafford boss revealed the injured quartet are also doubts for the Premier League trip to Portsmouth (Portsmouth 13/2 draw 100/30 Man United 1/3 match bets) on Saturday.

“They’re all out,” said Ferguson. “Really it’s a fight to get one of them for Saturday’s game [against Portsmouth]. But I have my doubts.”

The Scot revealed Gary Neville could come into contention on Wednesday if he comes through a training session in the morning unscathed.

Darron Gibson, Gabriel Obertan and Ji-sung Park are certain to start against Besiktas.

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